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About

What is ReMASH?

ReMASH is powered by Resmetirom, a revolutionary, first-in-class, liver-directed, thyroid hormone receptor-beta (THR-β) agonist, designed to treat non-cirrhotic MASH with moderate to advanced fibrosis (F2-F3). It is available as 60 mg, 80 mg, and 100 mg tablets.

What is ReMASH
How It Works

How It Works?

ReMASH which contains resmetirom works by selectively activating THR-β receptors in the liver, improving lipid metabolism, reducing hepatic fat, and lowering liver inflammation, without systemic side effects.

Mechanism of Action
  • Targets liver cells directly
  • Reduces hepatic steatosis
  • Promotes fibrosis regression
  • Improves lipid profile

Benefits

  • Reduces liver fat, inflammation and stiffness
  • Decreases liver fibrosis
  • Improves insulin sensitivity
  • Improves cardiovascular outcomes
  • Promotes better lipid control (LDL-C, triglycerides, Apo B)
  • Enhances the quality of life in MASH patients 
How It Works
Dosage & Usage Prescribed Strengths

Dosage & Usage Prescribed Strengths

Available in 60 mg, 80 mg, and 100 mg tablets

Administration

To be taken orally under physician supervision. Dosage is personalized based on patient weight and liver condition.

Important Note

Must be used along with a balanced diet and exercise plan for best results.

Safety & Monitoring

  • Nausea, diarrhoea, dizziness, abdominal pain and pruritus
  • Regular liver monitoring is recommended
  • Inform your doctor about any existing thyroid, liver, heart, or kidney issues
  • Not for use without prescription
Safety & Monitoring Mild side effects

About

What is ReMASH?

What is ReMASH

ReMASH is powered by Resmetirom, a revolutionary, first-in-class, liver-directed, thyroid hormone receptor-beta (THR-β) agonist, designed to treat non-cirrhotic MASH with moderate to advanced fibrosis (F2-F3). It is available as 60 mg, 80 mg, and 100 mg tablets.

How It Works

How It Works?

ReMASH which contains resmetirom works by selectively activating THR-β receptors in the liver, improving lipid metabolism, reducing hepatic fat, and lowering liver inflammation, without systemic side effects.

Mechanism of Action
  • Targets liver cells directly
  • Reduces hepatic steatosis
  • Promotes fibrosis regression
  • Improves lipid profile

Benefits

How It Works
  • Reduces liver fat, inflammation and stiffness
  • Decreases liver fibrosis
  • Improves insulin sensitivity
  • Improves cardiovascular outcomes
  • Promotes better lipid control (LDL-C, triglycerides, Apo B)
  • Enhances the quality of life in MASH patients
Dosage & Usage Prescribed Strengths

Dosage & Usage Prescribed Strengths

Available in 60 mg, 80 mg, and 100 mg tablets

Administration

To be taken orally under physician supervision. Dosage is personalized based on patient weight and liver condition. 

Important Note

Must be used along with a balanced diet and exercise plan for best results.

Safety & Monitoring

Safety & Monitoring
  • Nausea, diarrhoea, dizziness, abdominal pain and pruritus
  • Regular liver monitoring is recommended
  • Inform your doctor about any existing thyroid, liver, heart, or kidney issues
  • Not for use without prescription

The Growing Challenge of MASH

MASH (Metabolic dysfunction Associated Steatohepatitis) is a progressive liver disease that often develops silently.

  • It begins with fat in the liver (steatosis).
  • Over time, inflammation and cell injury cause fibrosis (scarring).
  • If untreated, it can progress to cirrhosis, liver failure, or cancer.
Why it matters
  • Many people are unaware that they have MASH until it has advanced.
  • Risk is higher in those with obesity, type 2 diabetes, or high cholesterol.
  • Early intervention can prevent severe complications.
What is ReMASH

The Growing Challenge of MASH

What is ReMASH

MASH (Metabolic dysfunction Associated Steatohepatitis) is a progressive liver disease that often develops silently.

  • It begins with fat in the liver (steatosis).
  • Over time, inflammation and cell injury cause fibrosis (scarring).
  • If untreated, it can progress to cirrhosis, liver failure, or cancer.
Why it matters
  • Many people are unaware that they have MASH until it has advanced.
  • Risk is higher in those with obesity, type 2 diabetes, or high cholesterol.
  • Early intervention can prevent severe complications.
How It Works

ReMASH - A Breakthrough in Liver Health

ReMASH (resmetirom) is designed to change the course of MASH.

Proven in clinical trials to:
  • Reduce liver fat significantly within months
  • Reverse or slow fibrosis progression
  • Improve insulin sensitivity and metabolic health
  • Lower harmful cholesterol and triglycerides
How It Works

ReMASH - A Breakthrough in Liver Health

ReMASH (resmetirom) is designed to change the course of MASH.

Proven in clinical trials to:
  • Reduce liver fat significantly within months
  • Reverse or slow fibrosis progression
  • Improve insulin sensitivity and metabolic health
  • Lower harmful cholesterol and triglycerides

A Treatment Backed by Science

The MAESTRO-NASH Phase 3 trial showed:

  • NASH resolution in up to 29% of patients with resmetirom 100 mg vs 9% on placebo
  • At least one stage improvement in fibrosis in up to 26% vs 14% on placebo
  • Reduction in LDL-C and triglycerides, supporting cardiovascular health
  • Well-tolerated with mostly mild gastrointestinal side effects such as nausea and diarrhoea
What is ReMASH

A Treatment Backed by Science

What is ReMASH

The MAESTRO-NASH Phase 3 trial showed:

  • NASH resolution in up to 29% of patients with resmetirom 100 mg vs 9% on placebo
  • At least one stage improvement in fibrosis in up to 26% vs 14% on placebo
  • Reduction in LDL-C and triglycerides, supporting cardiovascular health
  • Well-tolerated with mostly mild gastrointestinal side effects such as nausea and diarrhoea
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Choose Your Path

Patients

Learn about MASH, treatment expectations, and lifestyle support

Healthcare Professionals

Access trial data, dosing guidance, and prescribing resources

Important Safety Information

  • Not for use in patients with cirrhosis or decompensated liver disease
  • Common side effects include diarrhoea, nausea, abdominal pain, dizziness, constipation, and itching
  • Inform your doctor about all medicines, including statins and antidiabetics, before starting ReMASH
Prescribing Information
What is ReMASH

Important Safety Information

What is ReMASH
  • Not for use in patients with cirrhosis or decompensated liver disease
  • Common side effects include diarrhoea, nausea, abdominal pain, dizziness, constipation, and itching
  • Inform your doctor about all medicines, including statins and antidiabetics, before starting ReMASH
Prescribing Information Patient Information Leaflet